- #20 Fabio Quartararo (2026)
- #42 Alex Rins (2026)
Red Bull KTM Factory Racing (KTM)
- #31 Pedro Acosta (multi-tahunan)
- #33 Brad Binder (2026)
Honda Factory Team (Honda)
- #10 Luca Marini (2025)
- #36 Joan Mir (2026)
Red Bull KTM Tech 3 (KTM)
- #12 Maverick Vinales (multi-tahunan)
- #23 Enea Bastianini (multi-tahunan)
LCR Honda Idemitsu-Castrol (Honda)
- #5 Johann Zarco (2025)
- #35 Somkiat Chantra (2025) - debutan
Trackhouse Racing (Aprilia)
- #25 Raul Fernandez (multi-tahunan)
- #79 Ai Ogura (2026) - debutan
Pertamina Enduro VR46 Racing Team (Ducati)
- #49 Fabio di Giannantonio (2026)
- #21 Franco Morbidelli (2025)
Gresini Racing (Ducati)
- #73 Alex Marquez (2026)
- #54 Fermin Aldeguer (2026) - debutan
Prima Pramac Racing (Yamaha)
- #43 Jack Miller (2025)
- #88 Miguel Oliveira (2026).***